Cyclen是氮杂冠醚的类似物,为制备磁共振造影剂的前体物质,同时为制备有效的大环螯合物的中间体。
CAS:294-90-6
分子式:C8H20N4
分子量:172.27
纯度:98%
存储:Store at -20°C
Background:
Cyclen is the aza analogue of crown ether, used as a precursor for MRI contrast agents, and is an intermediate for the preparation of effective macrocyclic chelates[1].
[1]. Rashid HU, et al. Cyclen-based Gd3+ complexes as MRI contrast agents: Relaxivity enhancement and ligand design. Bioorg Med Chem. 2016 Nov 15;24(22):5663-5684.