Folipastatin is a fungal metabolite produced by A.
CAS:139959-71-0
分子式:C23H24O5
分子量:380.4
纯度:98%
存储:Store at -20°C
Background:
Folipastatin is a fungal metabolite produced by A. unguis and an inhibitor of phospholipase A2 (PLA2; IC50 = 39 μM). It inhibits release of arachidonic acid from rat polymorphonuclear leukocytes (IC50 = 24 μM). Folipistatin also inhibits radioligand binding to L-type calcium channels in porcine heart membranes (IC50 = 0.39 μM) but has no effect on contraction of taenia (IC50 = >100 μM).