Artemisinic acid is a sesquiterpene that has been isolated from A.
CAS：80286-58-4
分子式：C15H22O2
分子量：234.3
纯度：98%
存储：Store at -20°C

Background:

Artemisinic acid is a sesquiterpene that has been isolated from A. annua. It has been used in the synthesis of the antimalarial agent artemisinin . Artemisinic acid (50-400 µM) decreases triglyceride levels and glycerol-3-phosphate dehydrogenase (GPDH) activity in human adipose tissue-derived mesenchymal stem cells (hAMSCs) in a dose-dependent manner and inhibits adipocyte differentiation when used at a concentration of 200 µM. It reduces mRNA expression and protein levels of C/EBPα, C/EBPδ, and PPARγ as well as the ratio of phosphorylated JNK to JNK in hAMSCs. Artemisinic acid also decreases C/EBPα and HMG-CoA reductase mRNA expression and inhibits cholesterol synthesis and melanogenesis in human epidermal melanocytes.