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&delta12-Prostaglandin D2
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
&delta12-Prostaglandin D2图片
CAS NO:64072-89-5
规格:98%
分子量:352.5
包装与价格:
包装价格(元)
500ug电议
1mg电议
5mg电议
10mg电议

产品介绍
Prostaglandin D2 (PGD2) is one of the five primary enzymatic prostaglandins derived directly from PGH2.
CAS:64072-89-5
分子式:C20H32O5
分子量:352.5
纯度:98%
存储:Store at -20°C

Background:

Prostaglandin D2 (PGD2) is one of the five primary enzymatic prostaglandins derived directly from PGH2. PGD2 is produced abundantly in the CSF by the lipocalin-type PGD synthase, and in the periphery by myeloid cells including mast cells and basophils by a second, hematopoietic-type PGD synthase. PGD2 is chemically unstable, and its use and analysis is complicated by its short in vivo half-life. δ12-PGD2 is one of the initial chemical decomposition products of PGD2. δ12-PGD2 is an intermediate in the pathway leading to δ12-PGJ2, which is a cyclopentenone prostaglandin with antimitotic and carcinogenic activities. The metabolism of δ12-PGD2 involves addition of thiol nucleophiles, as is the case with the majority of cyclopentenone prostaglandins.