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15-keto Latanoprost(free acid)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
15-keto Latanoprost(free acid)图片
CAS NO:369585-22-8
规格:98%
分子量:388.5
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议

产品介绍
15-keto Latanoprost is a potential metabolite of latanoprost when administered to animals.
CAS:369585-22-8
分子式:C23H32O5
分子量:388.5
纯度:98%
存储:Store at -20°C

Background:

15-keto Latanoprost is a potential metabolite of latanoprost when administered to animals. 15-keto Latanoprost is also one of the common minor impurities found in commercial preparations of the bulk drug compound. Although much less potent that the parent compound latanoprost, 15-keto latanoprost still retains the ability to produce a small but measurable decrease (1 mm Hg) in the intraocular pressure of normal cynomolgus monkeys when administered at a dose of 1 µg/eye. 15-keto Latanoprost is also a miotic in the normal cat eye, causing an 8 mm Hg reduction in pupillary diameter at 5 µg/eye. Again, this is not as potent as many other F-type prostaglandins; for example, prostaglandin F2α will produce this degree of miosis at a dose of less than 1 µg/eye.