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CGP 77675
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CGP 77675图片
CAS NO:234772-64-6
规格:98%
分子量:443.5
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议
25mg电议

产品介绍
CGP 77675 is an inhibitor of Src family kinases (SFKs) that blocks the phosphorylation of peptide substrates and autophosphorylation of purified c-Src (IC50s = 5-20 and 40 nM, respectively).
CAS:234772-64-6
分子式:C26H29N5O2
分子量:443.5
纯度:98%
存储:Store at -20°C

Background:

CGP 77675 is an inhibitor of Src family kinases (SFKs) that blocks the phosphorylation of peptide substrates and autophosphorylation of purified c-Src (IC50s = 5-20 and 40 nM, respectively). It also inhibits the SFKs Lck and c-Yes with low nanomolar IC50 values. CGP 77675 is used to elucidate the role of SFKs in such processes as bone resorption, tight junction formation in epithelial cells, and allograft survival. It can also be used in combination with the GSK3 inhibitor CHIR99021 to maintain mouse embryonic stem cells.