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UMI-77
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
UMI-77图片
CAS NO:518303-20-3
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议
10mM * 1mL in DMSO电议

产品名称
UMI 77,UMI77
产品介绍

生物活性

UMI-77是一种选择性的Mcl-1抑制剂,Ki为490 nM,显示出对Bcl-2家族其他成员的选择性。

靶点信息

Mcl-1
490 nM(Ki)

化学数据

目录号A14222
作用机制Inhibitor (抑制剂)
M. Wt468.34
FormulaC18H14BrNO5S2
Purity>99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No.518303-20-3
SynonymsUMI 77,UMI77
SMILESC1=CC=C2C(=C1)C(=CC(=C2O)SCC(=O)O)NS(=O)(=O)C3=CC=C(C=C3)Br

溶解度

In vitro (25°C)DMSO92 mg/mL (196.43 mM)
WaterInsoluble
EthanolWarmed: 92 mg/mL (196.43 mM)
In vivo5% DMSO+30% PEG 300+dd H2O5 mg/mL
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

储备液配制

Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM21.35 mL106.76 mL213.52 mL
0.5 mM4.27 mL21.35 mL42.7 mL
1 mM2.14 mL10.68 mL21.35 mL
5 mM0.43 mL2.14 mL4.27 mL

*The above data is based on the productmolecular weight 468.34. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.