您好,欢迎来到化工原料网! [登录] [免费注册]
化工原料网
位置:首页 > 产品库 > INVIVO-0084
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
INVIVO-0084
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CAS NO:1429180-08-4
包装:50mg, 100mg, 250mg
规格:≥98%

产品介绍

INVIVO-0084, formerly known as Mutant IDH1 inhibitor, is a potent mutant IDH1 R132H inhibitor. INVIVO-0084 has CAS#1429180-08-4. INVIVO-0084 has no formal name. For the convenience of communication, we temporally name it as INVIVO-0084. The last 4 digits of its CAS number was used for name. INVIVO-0084 was reported in patent literature WO 2017213910 (Eli Lilly and Company) and WO 2013046136 (Novartis). References: Popovici-Muller J, Lemieux RM, Artin E, Saunders JO, Salituro FG, Travins J, Cianchetta G, Cai Z, Zhou D, Cui D, Chen P, Straley K, Tobin E, Wang F, David MD, Penard-Lacronique V, Quivoron C, Saada V, de Botton S, Gross S, Dang L, Yang H, Utley L, Chen Y, Kim H, Jin S, Gu Z, Yao G, Luo Z, Lv X, Fang C, Yan L, Olaharski A, Silverman L, Biller S, Su SM, Yen K. Discovery of AG-120 (Ivosidenib): A First-in-Class Mutant IDH1 Inhibitor for the Treatment of IDH1 Mutant Cancers. ACS Med Chem Lett. 2018 Jan 19;9(4):300-305. doi: 10.1021/acsmedchemlett.7b00421. eCollection 2018 Apr 12. PubMed PMID: 29670690; PubMed Central PMCID: PMC5900343.

纯度:≥98%

CAS:1429180-08-4