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(R)-nitro-Blebbistatin
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
(R)-nitro-Blebbistatin图片
CAS NO:1217619-62-9
规格:98%
分子量:323.3
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议

产品介绍
(R)-nitro-Blebbistatin is a more stable form of (+)-blebbistatin, which is the inactive form of (-)-blebbistatin.
CAS:1217619-62-9
分子式:C17H13N3O4
分子量:323.3
纯度:98%
存储:Store at -20°C

Background:

(R)-nitro-Blebbistatin is a more stable form of (+)-blebbistatin , which is the inactive form of (-)-blebbistatin . Prolonged exposure to blue light (450-490 nm) results in degradation of blebbistatin to an inactive product via cytotoxic intermediates, which may be problematic for its use in fluorescent live cell imaging applications. The addition of a nitro group stabilizes the molecule to circumvent its degradation by prolonged blue light exposure. (R)-nitro-Blebbistatin has the same stereochemistry as the inactive (+)-blebbistatin enantiomer.