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Budesonide
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Budesonide图片
CAS NO:51333-22-3
包装:50mg
规格:98%
市场价:592元
分子量:430.53

产品介绍
Anti-inflammatory corticosteroid
CAS:51333-22-3
分子式:C25H34O6
分子量:430.53
纯度:98%
存储:Store at -20°C

Background:

Budesonide is an anti-inflammatory corticosteroid [1].


Budesonide has shown the potent glucocorticoid activity and little mineralocorticoid activity. In addition, Budesonide has been reported to have a wide range of inhibitory activities against multiple cells types and mediators involved in allergic and nonallergic-mediated inflammatory. Besides, the anti-inflammatory action of budesonide has been revealed to contribute to the efficacy in asthma. Apart from these, orally inhaled budesonide has been found to be rapidly absorbed in the lungs and that peak concentration is typically reached within 20 minutes. The results have been exhibited that peak plasma concentration is achieved in about 1 to 2 h and the absolute systemic availability is 6%-13% after oral administration of budesonide [1].


参考文献:
[1] Ricardo Zollner1*, Eduardo Abib Junior1,2*, Luciana Fernandes Duarte2, Maurício Wesley Perroud2andAntonioRicardo Amarante2. Bioequivalency Study for Inhaled Drugs: A Pharmacodynamic Approac. Bioequivalence & Bioavailability