INVIVO-3345, formerly known as Mcl-1 Inhibitor-11, is a reversible covalent inhibitor for Mcl-1. INVIVO-3345 has improved water solubility from Mcl-1 Inhibitor-5. INVIVO-3345 has CAS#2012563-34-5. The last 4 digit of its CAS# is used in its name. References: Akcay G, Belmonte MA, Aquila B, Chuaqui C, Hird AW, Lamb ML, Rawlins PB, Su N, Tentarelli S, Grimster NP, Su Q. Inhibition of Mcl-1 through covalent modification of a noncatalytic lysine side chain. Nat Chem Biol. 2016 Nov;12(11):931-936. doi: 10.1038/nchembio.2174. Epub 2016 Sep 5. PubMed PMID: 27595327.
纯度:≥98%
CAS:2012563-34-5