您好,欢迎来到化工原料网! [登录] [免费注册]
化工原料网
位置:首页 > 产品库 > 6-Methylcoumarin
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
6-Methylcoumarin
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
6-Methylcoumarin图片
CAS NO:92-48-8
规格:98%
分子量:160.17
包装与价格:
包装价格(元)
1g电议
5g电议

产品介绍
6-Methylcoumarin是一种广泛用于化妆品的合成香料。
CAS:92-48-8
分子式:C10H8O2
分子量:160.17
纯度:98%
存储:Store at -20°C

Background:

6-Methylcoumarin is a synthetic fragrance widely used in cosmetics.


6-Methylcoumarin is reported to be almost nonphototoxic in epidermal tissue and cell culture phototoxicity test models. HaCaT cells are treated with 6-Methylcoumarin (1-105 nM) and/or UVA (5 J cm-2), and γ-H2AX is detected by immunofluorescence staining and western blotting 4hours after the treatments. 6-Methylcoumarin clearly produces γ-H2AX-positive cells under UVA irradiation from a concentration of 100 nM[1].



[1]. Toyooka T, et al. Phosphorylation of histone H2AX is a powerful tool for detecting chemical photogenotoxicity. J Invest Dermatol. 2011 Jun;131(6):1313-21.