Verubulin (MPC-6827) 是一种高效、广谱的微管阻断剂,具有体内外细胞毒活性,有前景成为治疗多种癌症的理想药物。
CAS:827031-83-4
分子式:C17H17N3O
分子量:279.34
纯度:98%
存储:Store at -20°C
Background:
Verubulin (MPC-6827) is a microtubule-disrupting agent with potent and broad-spectrum in vitro and in vivo cytotoxic activities, and acts as a promising candidate for the treatment of multiple cancer types[1].
Microtubule[1]
[1]. Kasibhatla S, et al. MPC-6827: a small-molecule inhibitor of microtubule formation that is not a substrate for multidrug resistance pumps. Cancer Res. 2007 Jun 15;67(12):5865-71.