MethADP 是一个特异性的 CD73 抑制剂。
CAS:3768-14-7
分子式:C11H17N5O9P2
分子量:425.23
纯度:98%
存储:Store at -20°C
Background:
MethADP is a specific CD73 inhibitor.
CD73[1].
MethADP (AMP-CP: 20 μM) causes a marked inhibition of adenosine formation (0.96±0.96 μM) compared to untreated controls (9.6±1.5 μM) in A498 and RT4 cells, and MethADP (100 μM) completely inhibits the adenosine formation[1].
[1]. Mohlin C, et al. Studies of the extracellular ATP-adenosine pathway in human urinary tract epithelial cells. Pharmacology. 2009;84(4):196-202.