diABZI STING agonist-1 (trihydrochloride) 是一个选择性的干扰素基因刺激受体 (STING) 的激动剂。
CAS:2138299-34-8
分子式:C42H54Cl3N13O7
分子量:959.32
纯度:98%
存储:Store at -20°C
Background:
diABZI STING agonist-1 (trihydrochloride) is a selective stimulator of interferon genes (STING) receptor agonist.
STING[1].
diABZI STING agonist-1 (trihydrochloride) activates secretion of IFNβ, IL-6, TNF, and KC/GROα (also known as CXCL1) in wild-type but not Sting-/- mice, confirming that diABZI STING agonist-1 (trihydrochloride) STING-dependent activation of type-I interferon and pro-inflammatory cytokines in vivo[1].
[1]. Ramanjulu JM, et al. Design of amidobenzimidazole STING receptor agonists with systemic activity. Nature. 2018 Nov 7.