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Adrenomedullin(AM)(22-52),human(22-52-Adrenomedullin(human))
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CAS NO:159899-65-7
规格:98%
分子量:3576.04
包装与价格:
包装价格(元)
500ug电议
1mg电议
5mg电议

产品介绍
Adrenomedullin(AM)(22-52),human为肾上腺髓质素(adrenomedullinreceptor)受体拮抗剂,同时在猫后肢血管床中,对降钙素基因相关肽(CGRP)受体也具有拮抗作用。
CAS:159899-65-7
分子式:C159H252N46O48
分子量:3576.04
纯度:98%
存储:Store at -20°C

Background:

Adrenomedullin (AM) (22-52), human is an adrenomedullin receptor antagonist, and also antagonizes the calcitonin generelated peptide (CGRP) receptor in the hindlimb vascular bed of the cat.


Adrenomedullin (AM) (22-52), human shows no effect on hindlimb perfusion pressure responses to adrenomedullin (ADM) at 120 nmol. However, Adrenomedullin (AM) (22-52), human selectively and reversibly decreases vasodilator responses to human calcitonin generelated peptide (hCGRP) at 30 nmol, with similar effect to that of CGRP antagonist[1].



[1]. Champion HC, et al. Adrenomedullin-(22-52) antagonizes vasodilator responses to CGRP but not adrenomedullin in the cat. Am J Physiol. 1997 Jan;272(1 Pt 2):R234-42.