MK-0249是一种有效的histamineH3受体拮抗剂，对人体H3受体的Ki值为1.7nM。
CAS：862309-06-6
分子式：C23H24F3N3O2
分子量：431.45
纯度：98%
存储：Store at -20°C

Background:

MK-0249 is a potent histamine H3 receptor antagonist, with Ki of 1.7 nM for human H3.

[1]. Brioni JD, et al. Discovery of histamine H3 antagonists for the treatment of cognitive disorders and Alzheimer’s disease. J Pharmacol Exp Ther. 2011 Jan;336(1):38-46.