N-acetyl LTE4 is the major inactive metabolite of LTE4 found in bile.
CAS:80115-95-3
分子式:C25H39NO6S
分子量:481.6
纯度:98%
存储:Store at -20°C
Background:
N-acetyl LTE4 is the major inactive metabolite of LTE4 found in bile. This route of metabolism is prominent in the rat, but of minor importance in humans. N-acetyl LTE4 is 100 times less potent than LTC4 as a vasoconstricting agent. In healthy human subjects urinary excretion of N-acetyl LTE4 is about 1.5 nmol/mol creatinine, which is considerably less than that of LTE4 (12 nmol/mol creatinine).