DS21360717 是一种有效、可口服的 FER 酪氨酸激酶抑制剂,IC50 值为 0.49 nM。具有抗肿瘤活性。
CAS:2304654-43-9
分子式:C21H23N7O
分子量:389.45
纯度:98%
存储:Store at -20°C
Background:
DS21360717 is a potent and orally active FER tyrosine kinase inhibitor, with an IC50 of 0.49 nM. Anti-cancer activity[1].
[1]. Taniguchi T, et al. Discovery of Novel Pyrido-pyridazinone Derivatives as FER Tyrosine Kinase Inhibitors with Antitumor Activity. ACS Med Chem Lett. 2019 Mar 15;10(5):737-742.