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Rubratoxin A
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Rubratoxin A图片
CAS NO:22467-31-8
规格:98%
分子量:520.5
包装与价格:
包装价格(元)
250ug电议
500ug电议

产品介绍
Rubratoxin A is a natural mycotoxin and competitive inhibitor of protein phosphatase 2A (PP2A; IC50 = 170 nM).
CAS:22467-31-8
分子式:C26H32O11
分子量:520.5
纯度:98%
存储:Store at -20°C

Background:

Rubratoxin A is a natural mycotoxin and competitive inhibitor of protein phosphatase 2A (PP2A; IC50 = 170 nM). It has no significant effect on several other phosphatases, including PP1, PP2B, and protein tyrosine phosphatase 1B. Rubratoxin A drives overphosphorylation of PP2A substrate proteins in cultured cells treated for three hours at 20 µM. It causes suppression of tumor metastasis and reduction of primary tumor volume in mouse xenografts.