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15(S)-Fluprostenol
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
15(S)-Fluprostenol图片
CAS NO:54276-24-3
规格:98%
分子量:458.5
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议

产品介绍
(+)-15(R)-Fluprostenol isopropyl ester is a prodrug (Travoprost) which is converted by esterase enzymatic activity in the cornea to yield the corresponding free acid.
CAS:54276-24-3
分子式:C23H29F3O6
分子量:458.5
纯度:98%
存储:Store at -20°C

Background:

(+)-15(R)-Fluprostenol isopropyl ester is a prodrug (Travoprost) which is converted by esterase enzymatic activity in the cornea to yield the corresponding free acid. The free acid, (+)-15(R)-fluprostenol, is a potent FP receptor agonist. The 15(R)-epimers of most prostaglandins are about 100 times less potent than the natural, 15(S)-isomers. However, the neighboring phenoxy group at C-16 reverses the absolute configuration at C-15 in the fluprostenol series; hence, 15(S)-fluprostenol is less active as an FP agonist than 15(R)-fluprostenol. The biology of 15(S)-fluprostenol has not been widely studied.