M-COPA is a golgi disruptor which inhibits cell surface expression of MET protein and the ADP-ribosylation factor 1 (Arf1) activation. M-COPA also inhibits angiogenesis through suppression of both VEGFR1/2 and nuclear factor-kappaB (NF-kappaB) signaling pathways. References: Alborzinia H, Ignashkova TI, Dejure FR, Gendarme M, Theobald J, Wolfl S, Lindemann RK, Reiling JH. Golgi stress mediates redox imbalance and ferroptosis in human cells. Commun Biol. 2018 Nov 28;210. doi: 10.1038/s42003-018-0212-6. eCollection 2018. PubMed PMID: 30511023; PubMed Central PMCID: PMC6262011.
纯度:≥98%
CAS:861718-91-4