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Pradigastat(LCQ-908)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Pradigastat(LCQ-908)图片
CAS NO:956136-95-1
规格:≥98%
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议
50mg电议
100mg电议

产品介绍
理化性质和储存条件


Name: Pradigastat (LCQ-908)
CAS#: 956136-95-1
Chemical Formula: C25H24F3N3O2
Exact Mass: 455.18206
Molecular Weight: 455.48121
Storage-20℃ for 3 years in powder form
-80℃ for 2 years in solvent
Technical InformationSynonym: LCQ908; LCQ-908; LCQ 908
Chemical Name: 2-((1s,4s)-4-(4-(5-((6-(trifluoromethyl)pyridin-3-yl)amino)pyridin-2-yl)phenyl)cyclohexyl)acetic acid
InChi Key: GXALXAKNHIROPE-CALCHBBNSA-N
InChi Code: InChI=1S/C25H24F3N3O2/c26-25(27,28)23-12-10-21(15-30-23)31-20-9-11-22(29-14-20)19-7-5-18(6-8-19)17-3-1-16(2-4-17)13-24(32)33/h5-12,14-17,31H,1-4,13H2,(H,32,33)/t16-,17+
SMILES Code: FC(F)(C1=NC=C(NC2=CN=C(C3=CC=C([C@H](CC4)CC[C@H]4CC(O)=O)C=C3)C=C2)C=C1)F
实验参考方法
In VivoPradigastat (LCQ-908) is a potent inhibitor of DGAT1, and has been used for the phase II clinical trials to treat diabetes and obesity[1].
References

[1]. Birch AM, et al. DGAT1 inhibitors as anti-obesity and anti-diabetic agents. Curr Opin Drug Discov Devel. 2010 Jul;13(4):489-96.