5a-Pregnane-3,20-dione是一种内源性的孕酮代谢物。
CAS:566-65-4
分子式:C21H32O2
分子量:316.48
纯度:98%
存储:Store at -20°C
Background:
5a-Pregnane-3,20-dione is the endogenous progesterone metabolite.
5a-Pregnane-3,20-dione decreases cell-substrate attachment, adhesion plaques, vinculin expression, and polymerizes F-actin in MCF-7 breast cancer cells[1].
[1]. Wiebe JP, et al. The endogenous progesterone metabolite, 5a-pregnane-3,20-dione, decreases cell-substrate attachment, adhesion plaques, vinculin expression, and polymerized F-actin in MCF-7 breast cancer cells. Endocrine. 2001 Oct;16(1):7-14.