UR-144 and XLR11 are potent synthetic cannabinoids (CBs) that have been identified as adulterants of herbal products.
CAS：1364933-69-6
分子式：C21H28FN3O2
分子量：373.5
纯度：98%
存储：Store at -20°C

Background:

UR-144 and XLR11 are potent synthetic cannabinoids (CBs) that have been identified as adulterants of herbal products.[1],[2] Azidoindolene 1 is structurally similar to UR-144, XLR11, and a number of additional synthetic CBs with a hydrazide linking the tetramethylcyclopropyl group to the aminoalkylindole group. The physiological and toxicological properties of this compound are not known. Typically, a tetramethylcyclopropyl group confers selectivity for the peripheral CB2 receptor, and the addition of substituents at the N1-amine of the aminoalkylindole group is necessary for high affinity at either CB1 or CB2.[3] This product is intended for forensic and research applications.

Reference：
[1]. Uchiyama, N., Kawamura, M., Kikura-Hanajiri, R., et al. URB-754: A new class of designer drug and 12 synthetic cannabinoids detected in illegal products. Forensic Science International 227(1-3), 21-32 (2013).
[2]. Uchiyama, N., Matsuda, S., Kawamura, M., et al. Two new-type cannabimimetic quinolinyl carboxylates, QUPIC and QUCHIC, two new cannabimimetic carboxamide derivatives, ADB-FUBINACA and ADBICA, and five synthetic cannabinoids detected with a thiophene derivative α-PVT and an opioid receptor agonist AH-7921 identified in illegal products. Forensic Toxicol. 31(2), 223-240 (2013).
[3]. Frost, J.M., Dart, M.J., Tietje, K.R., et al. Indol-3-ylcycloalkyl ketones: Effects of N1 substituted indole side chain variations on CB2 cannabinoid receptor activity. J. Med. Chem. 53(1), 295-315 (2010).