Mitapivat is a potent human R-type pyruvate kinase (PKR) inhibitor; also shows potency for mutant PKR including R510Q PKR, R532W PKR, T384W PKR etc.
CAS:1260075-17-9
分子式:C24H26N4O3S
分子量:450.55
纯度:98%
存储:Store at -20°C
Background:
Mitapivat is a potent human R-type pyruvate kinase (PKR) inhibitor; also shows potency for mutant PKR including R510Q PKR, R532W PKR, T384W PKR etc.
参考文献:
[1]. PYRUVATE KINASE ACTIVATORS FOR USE IN THERAPY. Patent WO/2012/151451A1