您好,欢迎来到化工原料网! [登录] [免费注册]
化工原料网
位置:首页 > 产品库 > 4-hydroxy Atorvastatin lactone
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
4-hydroxy Atorvastatin lactone
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
4-hydroxy Atorvastatin lactone图片
CAS NO:163217-70-7
包装:1mg
规格:98%
市场价:4422元
分子量:556.6

产品介绍
4-hydroxy Atorvastatin lactone is a metabolite of atorvastatin , an HMG-CoA reductase inhibitor present in formulations that have been used to treat hypercholesterolemia and certain dyslipidemias.
CAS:163217-70-7
分子式:C33H33FN2O5
分子量:556.6
纯度:98%
存储:Store at -20°C

Background:

4-hydroxy Atorvastatin lactone is a metabolite of atorvastatin , an HMG-CoA reductase inhibitor present in formulations that have been used to treat hypercholesterolemia and certain dyslipidemias. Atorvastatin is metabolized by the cytochrome P450 (CYP) isoform CYP3A4 to form 4-hydroxy atorvastatin and 2-hydroxy atorvastatin, which can be interconverted between their acid and lactone forms. Atorvastatin can itself be lactonized to atorvastatin lactone then metabolized by CYP3A4 directly to 4-hydroxy atorvastatin lactone and 2-hydroxy atorvastatin lactone.