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Dipraglurant
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Dipraglurant图片
CAS NO:872363-17-2
规格:98%
分子量:265.29
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议

产品介绍
mGluR5 antagonist
CAS:872363-17-2
分子式:C16H12FN3
分子量:265.29
纯度:98%
存储:Store at -20°C

Background:

Dipraglurant (ADX 48621) is a mGluR5 antagonists with IC50 of 0.021 μM. IC50 Value: 0.021 μM [1]Target: mGluRDipraglurant (ADX-48621) from Addex Therapeutics showed in vivo activity in different anxiety models in rat50 and is currently in phase II for the treatment of dyskinesia in Parkinson's disease.


参考文献:
[1]. The Synthesis and Use of Certain Pyridine Derivatives as Modulators of the G-protein Coupled Receptors mGlu5 and P2Y12