CAS NO: | 28845-86-5 |
包装: | 5mg |
规格: | 98% |
市场价: | 534元 |
分子量: | 334.54 |
Background:
Docosatrienoic acid is a rare ω-3 fatty acid; inhibits LTB4 binding to pig neutrophil membranes with an Ki of 5 μM.
Docosatrienoic acid inhibits LTB4 binding to pig neutrophil membranes with an Ki of 5 μM[1].
Application of docosatrienic acid dose-dependently decreases the peak K+ current amplitide and accelerates the potassium activation and inactivation kinetics at all rat membrane potentials[2].
[1]. Yagaloff KA, et al. Essential fatty acids are antagonists of the leukotriene B4 receptor. Prostaglandins Leukot Essent Fatty Acids. 1995 May;52(5):293-7. [2]. Krutetskaia ZI, et al. The effect of docosatrienoic acid on the potassium channels of outward rectification in the membrane of rat peritoneal macrophages. Fiziol Zh Im I M Sechenova. 1995 Jul;81(7):111-9.