CAS NO: | 115621-84-6 |
规格: | 98% |
分子量: | 440.53 |
包装 | 价格(元) |
1mg | 电议 |
5mg | 电议 |
10mg | 电议 |
20mg | 电议 |
Background:
PAF-AN-1 is a platelet activating factor receptor (PAF) antagonist.
PAF-AN-1 is extracted from patent EP0469477A1, page 2, line 47[1]. PAF-AN-1 is a 5-aryl-2,3-dihydroimidazo[2,1-a]isoquinoline analog. PAF-AN-1 inhibits PAF-induced bronchoconstriction and hemoconcentration when administered po to the guinea pig[2].
[1]. EP0469477A1 [2]. Houlihan WJ, et al. Structural modification of 5-aryl-2,3-dihydroimidazo[2,1-a]isoquinoline platelet activating factor receptor antagonists. J Med Chem. 1993 Oct 15;36(21):3098-102.