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Bisabolangelone
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Bisabolangelone图片
CAS NO:30557-81-4
规格:98%
分子量:248.32
包装与价格:
包装价格(元)
1mg电议
5mg电议

产品介绍
Bisabolangelone 是从 Osterici Radix 植物的根中分离出来的倍半萜衍生物。Bisabolangelone 具有抗炎作用,通过阻断巨噬细胞内的 NF-kappaB 和 MAPK 通路抑制脂多糖刺激的炎症。Bisabolangelone 具有抗溃疡作用。
CAS:30557-81-4
分子式:C15H20O3
分子量:248.32
纯度:98%
存储:Store at -20°C

Background:

Bisabolangelone, a sesquiterpene derivative, is isolated from the roots of Osterici Radix. Bisabolangelone possesses anti-inflammatory properties, which inhibits LPS-stimulated inflammation through the blocking of NF-kappaB and MAPK pathways in macrophages. Bisabolangelone has anti-ulcer activities[1][2].




[1]. Jung HW, et al. Bisabolangelone isolated from Ostericum koreanum inhibits the production of inflammatory mediators by down-regulation of NF-kappaB and ERK MAP kinase activity in LPS-stimulated RAW264.7 cells. Int Immunopharmacol. 2010 Feb;10(2):155-62. [2]. Wang J, et al. The anti-ulcer activities of bisabolangelone from Angelica polymorpha. J Ethnopharmacol. 2009 Jun 22;123(2):343-6.