Hexadimethrinebromide是一种聚合物,可增强逆转录病毒转导。
CAS:28728-55-4
分子式:C15H36Br2N2
分子量:404.27
纯度:98%
存储:Store at -20°C
Background:
Hexadimethrine bromide is a cationic polymer discovered to enhance retroviral transduction.
Hexadimethrine bromide inhibits human mesenchymal stem cell proliferation during lentiviral transduction. Hexadimethrine bromide is considered non-toxic at low concentrations, but has been found to negatively affect cell proliferation in some cell types at concentrations greater than 10 µg/mL. Trypsinized cells exposed to Hexadimethrine bromide are visibly larger in size when viewed under the microscope[1].
[1]. Lin P, et al. Polybrene inhibits human mesenchymal stem cell proliferation during lentiviral transduction. PLoS One. 2011;6(8):e23891.