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GDC-0927 Racemate(SRN-927 Racemate)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
GDC-0927 Racemate(SRN-927 Racemate)图片
CAS NO:1443983-36-5
规格:98%
分子量:461.52
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议
50mg电议

产品介绍
GDC-0927Racemate(SRN-927Racemate)是雌激素受体(estrogenreceptor)的降解剂,能够有效抑制ER-α的活性,IC50值为0.2nM,可用于雌激素受体有关的疾病。
CAS:1443983-36-5
分子式:C28H28FNO4
分子量:461.52
纯度:98%
存储:Store at -20°C

Background:

GDC-0927 Racemate (SRN-927 Racemate) is a degrader of estrogen receptor, potently inhibits ER-α activity, with an IC50 of 0.2 nM, and is used in the research of ER-related diseases.


GDC-0927 Racemate (Example 1) is a degrader of estrogen receptor, potently inhibits ER-α activity, with an IC50 of 0.2 nM, and is used in the research of ER-related diseases. GDC-0927 Racemate reduces the viability of MCF7 cells with an IC50 of 0.21 nM[1].



[1]. Mehmet Kahraman, et al. Estrogen receptor modulator and uses thereof. WO2014205138A1.