LEQ506是第二代smoothened(smo)抑制剂，在人类和小鼠中的IC50值分别为2和4nM。
CAS：1204975-42-7
分子式：C25H32N6O
分子量：432.56
纯度：98%
存储：Store at -20°C

Background:

LEQ506 is a second-generation inhibitor of smoothened (Smo) with IC50s of 2 and 4 nM in human and mouse, respectively.

LEQ506 is a second-generation inhibitor of smoothened (Smo) with IC50s of 2 and 4 nM in human and mouse, respectively. LEQ506 inhibits Hedgehog (Hh) signaling in a human cell line (HEPM) as measured by the amount of Gli mRNA with an IC50