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[Des-Arg9]-Bradykinin
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
[Des-Arg9]-Bradykinin图片
CAS NO:15958-92-6
规格:98%
分子量:904.02
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议

产品介绍
[Des-Arg9]-Bradykinin 是一种Bradykinin (B1) 受体激动剂,对 B1 受体选择性比B2 受体高。
CAS:15958-92-6
分子式:C44H61N11O10
分子量:904.02
纯度:98%
存储:Store at -20°C

Background:

[Des-Arg9]-Bradykinin is a Bradykinin (B1) receptor agonist that displays selectivity for B1 over B2 receptors.


The B2 receptor mediates the action of bradykinin (BK) and lysyl-bradykinin (Lys-BK), the first set of bioactive kinins formed in response to injury from kininogen precursors through the actions of plasma and tissue kallikreins, whereas the B1 receptor mediates the action of [Des-Arg9]-Bradykinin (des-Arg9-BK) and Lys-des-Arg Arg9-BK, the second set of bioactive kinins formed through the actions of carboxypeptidases on BK and Lys-BK, respectively[1].


参考文献:
[1]. Leeb-Lundberg LM, et al. International union of pharmacology. XLV. Classification of the kinin receptor family: from molecular mechanisms to pathophysiological consequences. Pharmacol Rev. 2005 Mar;57(1):27-77.