AdrenocorticotropicHormone(ACTH)(1-39),rat是一种有效的黑皮质素4型受体(melanocortin4receptor,MC4R)激动剂。
CAS:4037-01-8
分子式:C44H59N13O10S
分子量:962.09
纯度:98%
存储:Store at -20°C
Background:
Adrenocorticotropic Hormone (ACTH) (4-10), human is a melanocortin 4 (MC4R) receptor agonist.
Adrenocorticotropic Hormone (ACTH) (4-10), human (ACTH (4-10)) is the core sequence of all melanocortins and binds selectively to MC4-R. In humans, ACTH (4-10) enters the cerebral fluid compartment after intranasal application and leads to a decrease in total body fat after 6 weeks of continuous treatment[1].
[1]. Wellh?ner P, et al. Intranasal application of the melanocortin 4 receptor agonist MSH/ACTH(4-10) in humans causes lipolysis in white adipose tissue. Int J Obes (Lond). 2012 May;36(5):703-8.