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DPBQ
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
DPBQ图片
CAS NO:7029-89-2
规格:98%
分子量:362.38
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议

产品介绍
DPBQ是一种p53激活剂。
CAS:7029-89-2
分子式:C24H14N2O2
分子量:362.38
纯度:98%
存储:Store at -20°C

Background:

DPBQ is a p53 activator.


DPBQ elicits apoptosis and cell death and is selective for effects in 4N cells. DPBQ elicits expression and phosphorylation of p53 and this effect is specific to tetraploid cells. Knockdown of TP53 restores proliferation of tetraploid cells in the presence of DPBQ[1].



[1]. Choudhary A, et al. Identification of Selective Lead Compounds for Treatment of High-Ploidy Breast Cancer. Mol Cancer Ther. 2016 Jan;15(1):48-59.