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Maprotiline
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CAS NO:10262-69-8
规格:≥98%
包装与价格:
包装价格(元)
1g电议
2g电议
5g电议

产品介绍

Description: Maprotiline is a a tetracyclic antidepressant and a selective noradrenalin re-uptake inhibitor, used in the treatment of depression. Maprotiline inhibits HERG channels expressed in HEK cells with an IC50 of 5.2 μM and HERG channels expressed in oocytes with an IC50 of 24 μM. Maprotiline blocks open channels but has no significant effect on closed channels. Maprotiline is atetracyclic antidepressant, which strongly inhibits the uptake of noradrenaline, though it is notable in its lack of inhibition of serotonergic uptake.

References: Eur J Pharmacol. 2006 Feb 15;531(1-3):1-8; Cancer Lett. 2009 Apr 8;276(1):14-20.

Related CAS #: 10347-81-6 (HCl) 10262-69-8 (free)

纯度:≥98%

CAS:10262-69-8