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Mavelertinib(PF06747775)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Mavelertinib(PF06747775)图片
CAS NO:1776112-90-3
规格:≥98%
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议
50mg电议
100mg电议

产品介绍

Mavelertinib (formerly PF-06747775; PF06747775) is a mutant-selective, orally bioactive and irreversible/covalent inhibitor of the epidermal growth factor receptor (EGFR) T790M. It has potential antineoplastic activity. As as EGFR T790M inhibitor, PF-06747775 specifically binds to and inhibits EGFR T790M, a secondarily acquired resistance mutation, which prevents EGFR-mediated signaling and leads to cell death in EGFR T790M-expressing tumor cells. Compared to some other EGFR inhibitors, PF-06747775 may have therapeutic benefits in tumors with T790M-mediated drug resistance.

纯度:≥98%

CAS:1776112-90-3