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Bevenopran(CB-5945)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Bevenopran(CB-5945)图片
CAS NO:676500-67-7
规格:98%
分子量:386.44
包装与价格:
包装价格(元)
1mg电议
5mg电议

产品介绍
Bevenopran是一种外周μ阿片受体(μ-opioidreceptor)拮抗剂。
CAS:676500-67-7
分子式:C20H26N4O4
分子量:386.44
纯度:98%
存储:Store at -20°C

Background:

Bevenopran is a peripheral μ-opioid receptor antagonist.



Bevenopran is a peripheral μ-opioid receptor antagonist. Bevenopran is currently under investigation for the treatment of opioid-induced bowel dysfunction (OBD)[1]. Bevenopran tends to increase bowel movement (BM) frequency, especially for 0.1 mg twice daily and 4 mg daily, respectively[1].


[1]. Diego L, et al. Novel opioid antagonists for opioid-induced bowel dysfunction. Expert Opin Investig Drugs. 2011 Aug;20(8):1047-56. [2]. Siemens W, et al. Advances in pharmacotherapy for opioid-induced constipation - a systematic review. Expert Opin Pharmacother. 2015 Mar;16(4):515-32.