Secretoneurin, rat 是由分泌粒蛋白 II (SgII) 的蛋白水解过程产生的一种 33 个氨基酸多肽。Secretoneurin, rat 在体内和体外诱导大鼠纹状体多巴胺释放,对单核细胞和嗜酸性粒细胞有很强的趋化作用,而对粒细胞则没有。
CAS:149146-12-3
分子式:C159H252N40O58
分子量:3651.95
纯度:98%
存储:Store at -20°C
Background:
Secretoneurin, rat, a 33-amino acid polypeptide, is generated by proteolytic processing of secretogranin II (SgII). Secretoneurin, rat induces dopamine release in the rat striatum in vivo and in vitro, and it exerts a very strong chemotactic effect on monocytes and eosinophils but not on granulocytes[1].
[1]. Troger J, et al. Secretoneurin in the peripheral ocular innervation. Invest Ophthalmol Vis Sci. 2005 Feb;46(2):647-54.