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Dexloxiglumide
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Dexloxiglumide图片
CAS NO:119817-90-2
规格:98%
分子量:461.38
包装与价格:
包装价格(元)
100mg电议
50mg电议
1mg电议
5mg电议
10mg电议

产品介绍
Dexloxiglumide 是一种选择性的胆囊收缩素 A 型 (CCKA) 受体拮抗剂。Dexloxiglumide 是 Loxiglumide 的活性对映体,可抑制胆囊收缩素-八肽 (CCK-8) 诱导的平滑肌细胞收缩。
CAS:119817-90-2
分子式:C21H30Cl2N2O5
分子量:461.38
纯度:98%
存储:Store at -20°C

Background:

Dexloxiglumide is a selective cholecystokinin type A (CCKA) receptor antagonist[1]. Dexloxiglumide, the active enantiomer of Loxiglumide, inhibits smooth muscle cell contractions induced by cholecystokinin-octapeptide (CCK-8)[2].




[1]. Scarpignato C, et al. Effect of dexloxiglumide and spiroglumide, two new CCK-receptor antagonists, on gastric emptying and secretion in the rat: evaluation of their receptor selectivity in vivo. Aliment Pharmacol Ther. 1996 Jun;10(3):411-9. [2]. Maselli MA, et al. CCK1 receptor antagonist, dexloxiglumide: effects on human isolated gallbladder. Potential clinical applications. Minerva Gastroenterol Dietol. 2003 Sep;49(3):211-6.