2-Furoicacid(Furan-2-carboxylicacid)是一种有机化合物，经糠醛氧化得到。在大鼠试验中，2-Furoicacid具有抗血脂作用，能够降低血清中胆固醇和甘油三酯的水平。
CAS：88-14-2
分子式：C5H4O3
分子量：112.08
纯度：98%
存储：Store at -20°C

Background:

2-Furoic acid (Furan-2-carboxylic acid) is an organic compound produced through furfural oxidation[1]. 2-Furoic acid exhibits hypolipidemic effet, lowers both serum cholesterol and serum triglyceride levels in rats[2].

2-Furoic acid significantly reduces serum cholesterol and serum triglyceride levels[2]. 2-Furoic acid also lowers the liver and small intestine ATP dependent citrate lyase, acetyl CoA synthetase, acyl CoA cholesterol acyl transferase, sn-glycerol 3-phosphate acyl transferase, phosphatidylate phosphohydrolase and heparin induced lipoprotein lipase activities[2].2-Furoic acid shows the LD50 of 250 mg/kg i.p. in the acute toxicity studies in mice[2].

[1]. Wordofa GG, et al. Tolerance and metabolic response of Pseudomonas taiwanensis VLB120 towards biomass hydrolysate-derived inhibitors. Biotechnol Biofuels. 2018 Jul 19;11:199. [2]. Hall IH, et al. The hypolipidemic effects of 2-furoic acid in Sprague-Dawley rats. Arch Pharm (Weinheim). 1993 Jan;326(1):15-23.