BoNT-IN-1是一种有效的A型肉毒毒素轻链(BoNTALC)抑制剂,IC50值为0.9uM。
CAS:694443-03-3
分子式:C23H20N4O3
分子量:400.43
纯度:98%
存储:Store at -20°C
Background:
BoNT-IN-1 is a potent inhibitor of Botulinum neurotoxin A light chain (BoNTA LC) with IC50 of 0.9 uM.IC50 value: 0.9 uMTarget: BoNT in vitro: BoNT-IN-1 targets BoNT/A LC enzymatic activity,is highly efficient in vitro, BoNT-IN-1 has good property in cell-based, as well as tissue-based assays.
[1]. Caglic D, et al. Identification of clinically viable quinolinol inhibitors of botulinum neurotoxin A light chain. J Med Chem. 2014 Feb 13;57(3):669-676.