Reveromycin B is a spiroketal bacterial metabolite originally isolated from Streptomyces.
CAS:144860-68-4
分子式:C36H52O11
分子量:660.8
纯度:98%
存储:Store at -20°C
Background:
Reveromycin B is a spiroketal bacterial metabolite originally isolated from Streptomyces. It inhibits EGF-induced mitogenic activity in Balb/MK cells (IC50 = 6 μg/ml) and exhibits pH-dependent antifungal activity against C. albicans (MICs = 15.6 and >500 μg/ml at pH 3.0 and 7.4, respectively). Unlike reveromycin A and reveromycin C , reveromycin B does not inhibit proliferation of KB and K562 cells.