TTX-resistant Na+ currents inhibitor
CAS:23828-92-4
分子式:C13H18Br2N2O.HCl
分子量:414.56
纯度:98%
存储:Store at -20°C
Background:
AmbroxolHCl is a potent inhibitor of the neuronal Na+ channels, inhibits TTX-resistant Na+ currents with IC50 of 35.2 μM and 22.5 μM for tonic and phasic block, inhibits TTX-sensitive Na+ currents with IC50 of 100 μM. Phase 3.