AMG2850 是一个有效的、有口服活性的TRPM8 的选择性拮抗剂。
CAS：1470018-52-0
分子式：C19H17F6N3O
分子量：417.35
纯度：98%
存储：Store at -20°C
Background:
AMG2850 is a potent, orally bioavailable and selective transient receptor potential melastatin 8 (TRPM8) antagonist[1].
TRPM8[1].
[1]. Lehto SG, et al. AMG2850, a potent and selective TRPM8 antagonist, is not effective in rat models of inflammatory mechanical hypersensitivity and neuropathic tactile allodynia. Naunyn Schmiedebergs Arch Pharmacol. 2015 Apr;388(4):465-76.
m.cnreagent.com
