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Parasin I
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CAS NO:219552-69-9
规格:98%
分子量:2000.31
包装与价格:
包装价格(元)
500ug电议
1mg电议
5mg电议

产品介绍
ParasinI是一种由19个氨基酸残基组成的多肽,源于从鲶鱼皮肤分离到的组蛋白H2A,具有抗菌的作用。
CAS:219552-69-9
分子式:C82H154N34O24
分子量:2000.31
纯度:98%
存储:Store at -20°C

Background:

Parasin I is a 19-amino acid histone H2A-derived peptide isolated from the skin of the catfish, and shows antimicrobial activity.


Parasin I with comparable antimicrobial activities localized to the cell membrane and subsequently permeabilized the outer and cytoplasmic membranes. Parasin I and its active analogs show strong cytoplasmic membrane permeabilizing activity[1]. Codon optimized parasin I fused with human lysozyme is expressed in Pichia pastoris, and has potent antibiotic activity[2].



[1]. Koo YS, et al. Structure-activity relations of parasin I, a histone H2A-derived antimicrobial peptide. Peptides. 2008 Jul;29(7):1102-8. [2]. Zhao H, et al. Characterization of bioactive recombinant antimicrobial peptide parasin I fused with human lysozyme expressed in the yeast Pichia pastoris system. Enzyme Microb Technol. 2015 Sep;77:61-7.