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Rimeporide hydrochloride(EMD-87580 hydrochloride)
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Rimeporide hydrochloride(EMD-87580 hydrochloride)图片
CAS NO:187870-95-7
规格:98%
分子量:369.84
包装与价格：
包装价格(元)
1mg电议
5mg电议

产品介绍
Rimeporidehydrochloride(EMD-87580hydrochloride)是一种有效的选择性Na+/H+交换泵(NHE-1)抑制剂。
CAS：187870-95-7
分子式：C11H16ClN3O5S2
分子量：369.84
纯度：98%
存储：Store at -20°C

Background:

Rimeporide hydrochloride (EMD-87580 hydrochloride) is a potent and selective inhibitor of the Na+/H+ exchanger (NHE-1).


Blocking NHE-1 activity has been shown to decrease intracellular Na+ and Ca2+ overload and pH and Rimeporide (EMD-87580) represents a new therapeutic option for duchenne muscular dystrophy (DMD). Rimeporide (EMD-87580) is expected to act as a muscle-sparing agent and its mode of action means that it is mutation independent[1].



[1]. F.Porte-Thomé, et al. Development of Rimeporide, a sodium-hydrogen exchanger (NHE-1) inhibitor, for patients with Duchenne muscular dystrophy. Neuromuscular Disorders. October 2015 Oct 25:259-260.