BPN-15606 is a highly potent, orally bioavailable γ-secretase modulator (GSM). GSM attenuates the production of Aβ42 by SHSY5Y neuroblastoma cells. References: Wagner SL, Rynearson KD, Duddy SK, Zhang C, Nguyen PD, Becker A, Vo U, Masliah D, Monte L, Klee JB, Echmalian CM, Xia W, Quinti L, Johnson G, Lin JH, Kim DY, Mobley WC, Rissman RA, Tanzi RE. Pharmacological and Toxicological Properties of the Potent Oral γ-Secretase Modulator BPN-15606. J Pharmacol Exp Ther. 2017 Jul;362(1):31-44. doi: 10.1124/jpet.117.240861. Epub 2017 Apr 17. PubMed PMID: 28416568; PubMed Central PMCID: PMC5454592.

纯度：≥98%

CAS：1914989-49-3